Mets vs. Padres: 4/13/2009
Starting Pitchers: Mike Pelfrey (NYN) vs Walter Silva (SDN)
Score: 6-5 (SDN)
Attendance: 41,007
First Batter: Jody Gerut (SDN) (Homered to RF)

San Diego Padres center fielder Jody Gerut led off the first game at Citi Field with a home run, making it the only park to open with a homer (minimum 300 games). Johan Santana's no-hitter was the first ever thrown by a Mets pitcher and occurred in the team's 51st season and 8,020th game, which was the longest drought any franchise had endured before recording its first no-hitter. It took only three more years before the second no-hitter was thrown at Citi Field and the third was thrown less than four months later.